Hei! Her er en forklaring på disse to formene for vannansamlinger

Question: Four years ago I was diagnosed with fibromyalgia. This may seem petty but the most irritating problem associated with this disease is the tremendous swelling that I incur daily. For me, the swelling seems to worsen as the day goes on. Pants I put on in the morning do not fit me by the end of my work day. My legs and feet seem to be the most affected. I have gained weight, which I cannot lose. I exercise daily and have faithfully for 10 years. I am truly at my wits end. Can you offer any suggestions?

Dr. Lowe: Your complaints are not petty to me. If your swelling is a product of too little thyroid hormone regulation, it may only be the most obvious abnormality. Despite your normal thyroid test results (see part 2 below), your weight gain may be an effect of inadequate thyroid hormone regulation. And your swelling may be due to one of two other effects of the inadequacy.

One is what used to be termed "myxedema." This is swelling caused by an increase in water-binding molecules in the connective tissues. It results from inadequate thyroid hormone inhibition of the cells that produce the molecules. This occurs in some patients with hypothyroidism and others with thyroid hormone resistance. Awad in 1973, and Yaron and coworkers in 1997, provided research data that suggest some fibromyalgia patients have the connective tissue abnormality (increased hyaluronic acid) underlying myxedema. I have found myxedema in some fibromyalgia patients before treatment, and I've seen it disappear during their treatment with thyroid hormone. Skin and underlying tissues that are myxedematous do not "pit" when pressed into with a finger. If the tissue "pits," the swelling is more likely caused by fluid retention from another source. (Swelling of the wrist ligaments in hypothyroid patients can cause carpal tunnel syndrome.)

The other possible cause of swelling is an increase in the amount of fluid outside cells. This happens in the bodies of some patients who have deficient thyroid hormone regulation, and occurs because the blood vessels in the kidneys constrict in response to low blood pressure. The constriction of the vessels is water conserving. It reduces the amount of water lost to the urine and reabsorbs it into the circulation. The increased water in the blood helps prevent the blood pressure from further decreasing. Some of the fluid, however, is lost to the tissue spaces. This can result in swelling that may be distinguished by "pitting" when pressed into with a finger.

If either or both of these effects account for your swelling, they should disappear and cease occurring when you take a high enough dosage of the proper form of thyroid hormone.

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