Anti-thyroid Antibodies. Aarflot and Bruusgaard measured thyroid microsomal antibodies in 737 men and 771 women who ranged in age from 40-to-42 (19). Subjects with chronic widespread musculoskeletal complaints had a significantly higher incidence of antibodies than did subjects without such complaints (16.0% versus 7.3%, p<0.01). The prevalence of antibodies was significantly higher in women than men (20.4% versus 11.6%, p = 0.02). It is noteworthy, however, that laboratory thyroid function test results did not differ significantly between the two groups. The investigators wrote that their results suggest that patients with microsomal thyroid antibodies may have symptoms due to subnormal thyroid hormone regulation of cell function before thyroid gland dysfunction is detectable by tests of thyroid hormone and TSH levels. The researchers implied that many patients diagnosed with FMS may in fact have chronic, widespread pain due to impaired thyroid gland function revealed only by increased titers of thyroid microsomal antibodies. If this is true, then the incidence of primary hypothyroidism among FMS patients may be higher than the 10% to 13% suggested by measures of TSH and thyroid hormone levels.
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Men jeg skjønner jo stort sett ikke en dritt som vanlig.