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07-07-05, 14:32 #36
Kaiza!
Fant flee artikler om hyperparathyroidisme:
En fra 1999
http://jcem.endojournals.org/cgi/content/full/84/7/2278
"There is little debate about the primacy of surgery in the management of classical PHPT. Rather, the question has been what to do about the many patients with nonclassical disease. A 1990 NIH consensus conference (55) clearly recommended surgery for patients with significant adverse effects of PHPT, for patients with complicating coexistent illnesses, for younger patients, and for those in whom consistent long-term follow-up could not be assured. It allowed that conscientious surveillance may be justified in patients with minimal hypercalcemia and no adverse effects, but it recognized that for many patients, the time and expense involved in rigorous follow-up would outweigh the burden of surgery. Nine years later, the demonstrated prevalence of nonclassical symptoms and their reversibility, the evidence of "asymptomatic" but harmful effects reversible by surgery, and the accumulating evidence for surgical reduction of increased long-term mortality risk substantially strengthen the argument for surgery in such patients. For these reasons, parathyroidectomy should generally be recommended for patients with a secure diagnosis of PHPT, even in the absence of classical symptoms. "
Det er siden da kommet en artikkel fra Sverige om at disse pasienter har masse andre symptomer (andre enn benbrudd og nyresten).
(leter etter artikkelen)
http://www.neurology.org/cgi/content/abstract/60/4/626 om slag
Du har jo høyt blodtrykk fra hyperparathyreosen din
Det går an å få målt sitt vitamin D-innhold i blodet, siden lavt vitamin D gir høyt PTH og høy calcium.
http://edrv.endojournals.org/cgi/con...tract/22/4/477
http://jcem.endojournals.org/cgi/content/full/88/8/3499
http://jcem.endojournals.org/cgi/con...ract/90/4/2122
http://jcem.endojournals.org/cgi/con...ract/82/5/1522
Så en til concensus (=synsing av en gruppe som var på kongress sammen, kanskje på Hawaii eller at annet spennede sted):
http://jcem.endojournals.org/cgi/con...ull/87/12/5353
og til en nyere artikkel
http://jcem.endojournals.org/cgi/content/full/88/7/3011
nora


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