Paul told me:
Many people do not understand conversion of T4. They think adding T3 will simply give them more T3. It doesn't work like that at all. This too is in my book. Even doctors do not understand it. Sometimes if they add T3 they want to reduce T4 - this is a mistake.

Adding T3 will reduce TSH. The liver uses TSH to determine T4 to T3 conversion rate. With a high TSH you get maximum T4 conversion rate to T3. With a low TSH you get the minimum conversion rate. Once TSH is zero the conversion rate cannot get lower and adding more T3 or T4 then always adds more T3 (but it could also add more reverse T3 - this is a different issue).
I am pretty sure I am on an too low dose with NDT/thyroid right now. The latest days I have felt cold, cold hands and feet. And ofcourse, the fatigue. Oh, yes, i have been here several times before. Why do I not discover it a bit earlier? I increase my dose.

And my early morning dose or late nightdose is going to be 1.5 grain or 90 mg NDT/Thyroid. It will contain 12.13.5 mcg with T3. 0.5 grain or 1 grain is a too low dose. The target is to make a change in the adrenals, and then it has to be enough T3.

Today I have also learned that people respond different on LDN. Some people have to lower their thyroidmedication. But other have to increase it! So I have to be observant for anything to happend now as an LDN'er