Thank you for your answer, Paul! I have ordered your book and are looking forward to understand more of this. It is a lot of new information for me. I must confess I have already started to take a bit of my NDT early in the morning/late night in two nights, around five o'clock. But one of my problems is sleeplessness. So I decided to just wake up by myself and take the pill. I am a little bit afraid of disturbing my precious sleep by new patterns. But on the other side my function is not satisfaing as it is now, so I am looking in all directions for new answers. I am also looking at LDN. I will see my doc next week, and I hope he are willing to give me LDN.