Lægen lyver om Thyroid USP

[Ruth Roland]

Jeg pleier ikke skrive her. Men er en flittig leser. Det som denne endokrinologen skriver gjorde meg så sjokkert at jeg måtte kontakte Henry Knafo hos Erfa Thyroid i Canada for å høre hva han hadde å si.

Da jeg intervjuet ham i sommer sa han følgende:

RR: Does the tablet content vary from batch to batch? If so, what is the maximum size of the differences?

HK: Like anything in nature, there are small variations from batch to batch. Although a variation of 10% is permitted by health Canada we rarely exceed 5% variation from batch to batch. The clinical significance of such a variation is minimal and should not distract someone from being treated with desiccated thyroid.

Jeg sendte ham en link til denne endokrinologens nettside og spurte på nytt "How are these number changing from batch to batch in Erfa Thyroid?"

Han svarer

Dear Mrs Roland,

Obviously the “big red book” doesn’t mention which kind of desiccated thyroid nor when this was true. The truth is that this was true 100 years ago when desiccated thyroid was discovered since then things have changed in the manufacturing process. In each Erfa 60 mg tablet embos*sed “ECI 60”, there is 36 mcg. of T4 and 8 mcg. of T3 . A 10% variation is accepted through the manufacturing process but we rarely exceed 5%.

I hope this helps.

Sincerely,



Henri Knafo, MD, MSc, BSc
Medical Director
Erfa Canada Inc

Jeg spør så om jeg får lov til å publisere dette på Sonjas Stoffskifteforum samt på bloggen min, og han svarer

Dear Mrs Roland,

No problem. You can also publish this:

Thyroid is a medication approved by Health Canada and is subject to inspection and standards as all the other medication in Canada. Thyroid medication was previously owned by Pfizer Canada and we did not change the formulation since then. As most of the medication, we follow the USP standards and consistency is preserved from batch to batch. Although the accepted difference in dosage between batch to batch is around 10%, we rarely exceed 5% variation which is in my opinion an excellent result. We also never had any recalls of the product contrarily to many levothyroxine products.

Sincerely,

Henri Knafo, MD, MSc, BSc
Medical Director
Erfa Canada Inc