Tenkte jeg skulle samle litt av den informasjonen jeg har lett fram om binyreproblemer kombinert med lavt stoffskifte. Flott hvis andre også kan bidra!

P.S. Jeg har oversatt teksten til norsk lenger ned i tråden!


1. SYMPTOMER

Først noen sitater fra Mary Shomon's bok "Living Well with Hypothyroidism" (HarperResource, New York 2005 (2. utg.) - ISBN 0-06-074095-7 - paperback):

- The Adrenal Connection (side 240-43)
One common condition that frequently accompanies hypothyroidism - and may even prevent proper treatment if it is not addressed itself - is adrenal exhaustion, also known as adrenal fatigue.

(...)

Adrenal fatigue often develops after periods of intense or lengthy physical or emotional stress, when overstimulation of the glands leaves them unable to meet your body's needs. (...) Symptoms include:

  • Excessive fatigue and exhaustion
    Nonrefreshing sleep (you get sufficient hours of sleep, but wake fatigued)
    A feeling of not being restored after a full night's sleep or having sleep disturbances
    Feeling overwhelmed by or unable to cope with stressors
    Feeling run down or overwhelmed
    Craving salty or sweet foods
    Feeling most energetic in the evening
    Low stamina, slow to recover from exercise
    Slow recovery from injury, illness, or stress
    Difficulty concentrating, brain fog
    Poor digestion
    Low immune function
    Food or environmental allergies
    Premenstrual syndrome or difficulties that develop during menopause
    Consistent low blood pressure
    Extreme sensitivity to cold
    Lack of sex drive
    Dark circles under the eyes
    Lines of dark pigment in the nails
    Startling easily
    No stamina for confrontation


Interestingly, one of the most common symptoms, according to some practitoners, is a lack of response to thyroid hormone replacement in people with hypothyroidism.

At his website - www.drrind.com - Dr. Bruce Rind, an expert on the thyroid-adrenal connection, has a helpful chart called the Metabolic Scorecard: Symptom Matrix with more information on adrenal symptoms. Dr. Rind feels that hypothyroidism and adrenal problems are very interrelated. Says Rind:
I've found that one of the strongest stressors to the adrenals is thyroid hormone (specifically T3). The body is designed so that under normal conditions, one organ will not destroy another. The thyroid energy is allowed to rise only to a level that will not harm the adrenals. Thus, in a stress situation, the tolerance of the adrenals usually drops and we see a corresponding drop in T3. Conversely, if fatigued adrenals just started to receive support (e.g., nutrients favorable to adrenal health, drastic reduction in stress, or even a very joyful situation) we see a rapid rise in T3. I find that most people with history of Grave's disease or Hashimoto's Thyroiditis demonstrate weakened adrenals. Thus, the success of the thyroid therapy is limited by the health of the adrenals.

(...)

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Her er det som står om det samme temaet i Richard L. Shames og Karilee Halo Shames' bok "Thyroid Power - 10 Steps to Total Health" (HarperResource, New York, 2002 (2. utg.) - ISBN 0-06-008222-4 - paperback):

The Thyroid-Adrenal Connection (s. 132)
A major connection exists between low thyroid and low adrenal. Low adrenal, also called adrenal insufficiency, can actually cause someone's thyroid problem to be much worse than it would be otherwise.

Crucial Reasons for Knowing Your Adrenal Levels (s. 133-134)
Adrenal insufficiency symptoms include: weakness, lack of libido, allergies, dark circles under the eyes, muscle and joint pain, dizziness, low blood pressure, low blood sugar, food and salt cravings, poor sleep, dry skin, cystic breasts, lines of dark pigment in the nails, difficulty recuperating from stresses such as colds or jet lag, no stamina for confrontation, tendency to startle easily, lowered immune function, anxiety, depression, and premature aging. Some of these symptoms are similar to those of low thyroid.

If low thyroid people with these symptoms are put on thyroid hormone alone, they sometimes respond negatively. They may have coexistent but hidden low adrenal. If they take thyroid hormone by itself, the resultant increased metabolism may accelerate the low adrenal problem. The proper approach in this case is to treat the patient with thyroid and adrenal support simultaneously.

Adrenal insufficiency, especially when unmasked by the addition of thyroid hormone, is unpleasant and uncomfortable. To compound the problem, the doctor and patient then may wrongly assume that thyroid replacement has been a mistake. A tremendous opportunity for better health has now been missed.

While uncomfortable, this dilemma can become a diagnostic tool. The doctor could then gradually add thyroid and adrenal hormone together, with the patient eventually taking optimal levels of both. This careful attention and delicate calibration are demanding on the practitioner and patient. Nevertheless, we have seen patient after patient dramatically improve with such dedication.

Also, interactions among your hormones are sometimes as important as the direct action of the hormone itself. Some adrenal hormones assist in the conversion of T-4 to T-3 and perhaps assist in the final effect of T-3 on the tissues. Some scientists believe that even the entrance of thyroid hormone into our cells is under the influence of adrenal hormones. Thus, if your adrenal level is high enough, you might do well to take both adrenal and thyroid hormone together.

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(Her er et intervju Mary Shomon har gjort på www.thyroid-info.com med 'Drs. Shames' om dette temaet.)


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Her har jeg klippet fra en artikkel online;

ADRENAL PROBLEMS (Replacement Cortisone Therapy)

By Dr Barry Durrant-Peatfield MB, BS, LRCP, MRCS (forfatter av boken "The Great Thyroid Scandal" - se link lenger ned).


The adrenals sit just above the kidneys and most of us have heard that these are responsible for the “fight or flight” reaction to stress. Briefly, there is a rapid increase of the glucocorticoids, to enable the body to cope. It is the failure of this mechanism to work properly, in the presence of general stress, or the stress of illness, that we are concerned with in the use of replacement cortisone therapy. We call this condition Low Adrenal Reserve, or simply, Adrenal Insufficiency.

The most severe form of the syndrome is called "Addisons Disease", after the great Guys Physician, Thomas Addison, who was the first to describe it in 1855. It was then usually due to tuberculosis destroying the glands. Patients were dusky coloured, with terrible weakness, malnutrition, collapse and coldness, and the illness ran a fatal course. It is pretty rarely seen in clinical practice. But we are concerned with the mild form of deficiency, where the patient may be well, until subjected to stress and/or illness. Then, many of the symptoms may appear with prostration and collapse; or there may be level of insufficiency present all the time, with varying degrees of weakness, muscle and joint pains, and general ill health.

So what do we look for in the way of symptoms? It is rarely clear cut, because the deficiency is so often part of another illness, and may therefore have something of the symptoms of both. We are particularly concerned with thyroid deficiency, which, if of longstanding, or fairly severe in degree, is most often associated with adrenal insufficiency, as well as a direct result of the stress on the system low thyroid function will cause.

The patient will complain of weakness and episodes of prostration, frequently feeling quite unwell without being able to pinpoint the cause. Episodes of dizziness, sometimes cold sweats, caused by the blood sugar becoming abnormally low, are not uncommon. Often, an odd internal shivering is described. Aches and pains of a rheumatic nature are other frequent complaints. The patient often complains of the cold, and is likely to be cold to the touch. The subject does not feel well, and may look ill, with dark rings under the eyes, and a general pallor. There are likely to be digestive problems, with excessive wind and bloating, and bowel disturbances. The menstrual cycle may be disturbed, or absent and libido low. Depression and anxiety may also be a feature. Some of the symptoms complained of by patients with M.E. -- Myalgic Encephalitis -- are very similar, leading to the well-grounded suspicion that M.E. is associated with low adrenal reserve. Certainly, frequent minor illnesses are common, with an overlong course of quite minor infections, which may also have an unusually severe effect on the patient.

Low thyroid function has some of these features, and it may be difficult to distinguish one from the other; In fact it should not be necessary because, as I pointed out above, as the two are often together, so too must the treatment overlap and be designed to relieve both.

The complications of treating hypothyroid or underactive thyroid patients, is that their consequent poor adrenal reserve may become suddenly obvious, as soon as the thyroid is treated. The thyroid supplementation may, at worst, precipitate the adrenal problem; but what usually happens, is that the thyroid replacement may either not apparently work at all, or the patient may have thyroid over dosage symptoms on quite a low level of replacement. Hence, where low adrenal reserve is suspected, it is possibly dangerous, and certainly ill advised, to treat the patient without supplementation of the adrenals, in the manner explained further below.