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Day 1-3: 2.5 mg first thing in the AM (2.5 mg total)
Day 4-6: 2.5 mg first thing, 2.5 mg in four hours (5 mg total)
Day 7-9: 2.5 mg first thing; 2.5 mg in four hours; 2.5 mg in four hours (7 1/2 mg total)
Day 10-12: 5 mg first thing; 2.5 mg in four hours; 2.5 mg in four hours (10 mg total)
Day 13-16: 5 mg first thing; 5 mg in four hours; 2.5 mg in four hours; 2.5 mg bedtime (15 mg total)
Day 17-20: 10 mg first thing; 5 mg in four hours; 2.5 mg in four hours; Bedtime 2.5 mg (20 mg total)
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NOTE: in some patients, the above scheduling causes on overreaction of the HPA axis which causes uncomfortable reactions when trying to raise. That knowledge is changing the way some patients and doctors are using cortisol–namely, they are “starting” right on 20 mg – 30 mg—the latter if the adrenal fatigue is quite severe.
Below are three methods for starting directly on HC without ramping. All are dosed at 8 am, noon, 4 pm and bedtime. By observation, we are seeing most needing the 25 – 30 mg. starting dose.
For 20 mgs (mild adrenal fatigue): 7.5 – 5 – 5 – 2.5
For 25 mgs (moderate adrenal fatigue): 10 – 7.5 – 5 – 2.5
For 30 mgs (severe adrenal fatigue, Stage 5 or higher: 10 – 10 – 5 – 5
Starting right on 20 mg can be successful for most if you do not have a high T3. Additionally, some patients may find they need to dose every 3 hours rather than 4 if the cortisol appears to run out with low cortisol symptoms before your next dose.