Retningslinjer for dosering av levotyroksin ved lavt stoffskifte hos barn

Medlibrary.org: Infants and Children

Levothyroxine therapy is usually initiated at full replacement doses, with the recommended dose per body weight decreasing with age (see Table 3). However, in children with chronic or severe hypothyroidism, an initial dose of 25 mcg/day of levothyroxine sodium is recommended with increments of 25 mcg every 2-4 weeks until the desired effect is achieved.

Hyperactivity in an older child can be minimized if the starting dose is one-fourth of the recommended full replacement dose, and the dose is then increased on a weekly basis by an amount equal to one-fourth the full-recommended replacement dose until the full recommended replacement dose is reached.

Table 3: Levothyroxine Sodium Dosing Guidelines for Pediatric Hypothyroidism

AGE	Daily Dose Per Kg Body Weight*
0-3 months	10-15 mcg/kg/day
3-6 months	8-10 mcg/kg/day
6-12 months	6-8 mcg/kg/day
1-5 years	5-6 mcg/kg/day
6-12 years	4-5 mcg/kg/day
>12 years but growth and puberty incomplete	2-3 mcg/kg/day
Growth and puberty complete	1.7 mcg/kg/day
*The dose should be adjusted based on clinical response and laboratory parameters

Source: / Kilde: Medlibrary.org
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• IKKE bruk fluortannkrem og andre fluorerte pleieprodukter fordi fluor forårsaker eller forverrer hypotyreose.
• Gi ikke barna rosiner og svart te fordi de inneholder store mengder fluor.

• Do NOT treat children's teeth with fluoride toothpaste and other fluorinated care products because fluoride causes or worsening hypothyroidism.
• Give NOT your children raisins and black tea because they contain high amounts of fluorine.